With the change of the times, there are more and more types of granulators, and the scale of the entire industry is expanding. However, the granulator is closely related to drug quality. Equipment upgrades must start from the pharmaceutical production needs and production standards, carry out structural adjustments, fully consider various problems that are prone to occur in drug production, and ensure pharmaceutical safety. After a period of application, the stability of the granulator will decrease. What are the specific manifestations?
The Selection of Materials and Processing Technology
The selection of materials and processing technology will affect the stability of dry granulators. It is not known that many equipment, due to excessive pressure during granulation, the rollers are very prone to wear, damage, and other conditions after a period of application, causing inconvenience and damage to the company.
The Equipment Design Is Relatively Simple
Many manufacturers design the equipment very simply without considering the problem of dust particles. As traditional Chinese medicine particles are prone to moisture absorption and stickiness, the materials are very easy to accumulate and block the passage on the granulator, causing pollution to the production environment and endangering the safety of drugs. The cleaning of the equipment also becomes more and more complicated.
More Fine Powder, Low Yield of Finished Products
After the application, many rollers contain more fine powder in the particles formed by pressing the materials into flakes, resulting in a low yield of finished products.
Double Screw Extruder is mainly used for filling, blending, modification, augmentation, chlorination, polypropylene, and processing of highly hygroscopic resins for rubber and plastic, and engineering resins.
Regular Inspections
The engine, transmission system, and adjustment device of the Double Screw Granulator should be regularly checked, such as the consumption of engine oil and lubricating oil. If the consumption rate is too fast, whether the fastening bolts and connecting bolts of the transmission components are loose, whether various transmission shafts and gears are normal, whether there is excessive noise, and whether the operation is normal, etc.
Regular Replacement of Parts
For the Double Screw Granulator, regular inspection and replacement of parts should be performed, including replacing lubricating oil, cleaning the cooling system, replacing air filters, checking the wear of the screw center and cylinder wall, and replacing fuel injectors and fuel filters, etc.
Regular Maintenance of Mechanical Parts
During the operation of the Double Screw Granulator, regular maintenance of mechanical parts should be carried out. For screw mechanical parts, timely inspection, cleaning, and replacement of friction pairs, inspection of transmission shafts, bearings, and other components should be performed to ensure the normal operation of the machine.
Check the Safety Circuit
The safety circuit of the Double Screw Granulator should be checked, such as the rotor protection circuit, cut-off protection circuit, three-phase load imbalance protection circuit, etc., to ensure the normal operation of the machine.
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